Prioritizing environmental risk of prescription pharmaceuticals
نویسندگان
چکیده
منابع مشابه
Improving environmental risk assessment of human pharmaceuticals.
This paper presents 10 recommendations for improving the European Medicines Agency's guidance for environmental risk assessment of human pharmaceutical products. The recommendations are based on up-to-date, available science in combination with experiences from other chemical frameworks such as the REACH-legislation for industrial chemicals. The recommendations concern: expanding the scope of t...
متن کاملThe Read-Across Hypothesis and Environmental Risk Assessment of Pharmaceuticals
Pharmaceuticals in the environment have received increased attention over the past decade, as they are ubiquitous in rivers and waterways. Concentrations are in sub-ng to low μg/L, well below acute toxic levels, but there are uncertainties regarding the effects of chronic exposures and there is a need to prioritise which pharmaceuticals may be of concern. The read-across hypothesis stipulates t...
متن کاملRisk Mitigation Measures: An Important Aspect of the Environmental Risk Assessment of Pharmaceuticals
Within EU marketing authorization procedures of human and veterinary medicinal products (HMP and VMP), an environmental risk assessment (ERA) has to be performed. In the event that an unacceptable environmental risk is identified, risk mitigation measures (RMM) shall be applied in order to reduce environmental exposure to the pharmaceutical. Within the authorization procedures of HMP, no RMM ha...
متن کاملPotential impact of pharmaceuticals on environmental health.
1 Environmental Processes and Water Technology Research Unit, Department of Environmental Science and Technology, Imperial College, London, London SW7 2AZ, England. Correspondence should be sent to Dr Voulvoulis at this address (email: [email protected]). Ref. No. 03-006189 For much of the last thirty years, research on the effects of chemical pollution of the environment has focused ...
متن کاملOccurrence and preliminarily environmental risk assessment of selected pharmaceuticals in the urban rivers, China
Twelve selected pharmaceuticals including antibiotics, analgesics, antiepileptics and lipid regulators were analysed and detected in water samples collected from 18 sampling sections along the three main urban rivers in Yangpu District of Shanghai, China during four sampling campaigns. Besides, algal growth inhibition test was conducted to preliminarily assess the eco-toxicology induced by the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Regulatory Toxicology and Pharmacology
سال: 2013
ISSN: 0273-2300
DOI: 10.1016/j.yrtph.2012.07.003